Schizophrenia is a major mysterious, serious mental illness that affects humans. Schizophrenia affects only a small percentage of people among adults. This illness affects more men than women as men respond worse towards the neuroleptic treatments. There are still no satisfactory answers for the cause of this illness. Some studies suggest that adverse emotional as well as physical experiences may cause schizophrenia.

Let us have an etiology of schizophrenia to know more about this illness. The major reason for schizophrenia is reversion of the sexual energy as well as the ego. The mind reverses itself to the state of infancy as well as self-love. Normal heterosexual love will not be supportive enough for the adult patients to adjust with their social responsibility. Over secretion of hormones from sexual glands can cause accumulation of the stimulating chemicals, inside digestive systems of hormones. This can cause schizophrenia.

Studies conducted on schizophrenia patients convinced many leading psychologists to believe that heredity also causes schizophrenia. Trauma during the birth can also be a reason for schizophrenia. Schizophrenia patients’ direct biological relatives carry a greater risk of getting schizophrenia unlike others. Only a meagre percentage of Second degree as well as third degree relatives of schizophrenia patients inherits the schizophrenia. Good percentage of monozygotic twins has more chance for getting schizophrenia unlike the dizygotic twins.

Maladjustment of the body towards a new environment can cause schizophrenia as it can lead to reversion of life force as well as emotional complexes. The amount as well as kind of stresses that an individual undergoes over a period can lead to schizophrenia. Among children, infections in the viral central nervous system pose greater risk of getting schizophrenia.

Conflict between the masculine as well as feminine elements of an individual is a cause for schizophrenia as per Neo Freudian Otto Rank’s studies. Those who find suitable as well as acceptable expression for their instincts related to the self-respect are prone to schizophrenia. Those who are having introvert nature are more susceptible.

Studies show that many dead schizophrenic patients had abnormalities in the structure of brains. Many of the schizophrenic patients have their cranial ventricles in enlarged state. Some of the patients have rather unique cortical laterality accompanied by dysfunction in left hemisphere of the brain. There is significant amount of gray matter loss in the brains of schizophrenic patients.

Defects related to the biochemical reactions that regulates the activities of GAD1 genes can lead to schizophrenia.GAD1 is an important gene which has big role in the production of an important chemical messenger with in human brain. Generally, GAD1 turns on at rather higher rates during prefrontal cortex development. However, in schizophrenia patients the increase in GAD1 is rather at lower rates. Oligogenic inheritance and polygenic inheritance are two type of additive effects related to genes which causes human vulnerability to schizophrenia. Some other risk factors related to schizophrenia include poor nutrition, exposure to certain influenza, exposure to war zones, poverty, incompatibility in Rh factor of blood, and depression. Detailed etiology schizophrenia will give better idea about schizophrenia.